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Meet Lisa Young

Lisa Young

Dr. Lisa Young, associate professor of pediatrics and medicine at Vanderbilt University, is a recipient of an R01 research grant from the National Institutes of Health to study pulmonary fibrosis for patients battling Hermansky-Pudlak Syndrome. HPS is an inherited disease, in which nearly all affected adults develop fatal pulmonary fibrosis. The known genetic causes of HPS provide a promising opportunity to study alveolar epithelial cell dysfunction, which Dr. Young recently demonstrated is the primary driver of fibrotic susceptibility in HPS. Dr. Young will use mouse models to understand what causes pulmonary fibrosis in HPS and how new therapies might be developed.

Dr. Young’s pathway toward the NIH grant on HPS began in 2007 with a joint ATS Foundation/ Hermansky-Pudlak Syndrome Network grant of $100,000. She used the results from the study to secure further funding from the Parker B. Francis Foundation and the NIH through a K08 mentored clinical scientist research career development award. The subject of her early research grant was “Alveolar Cell Dysfunction in Pulmonary Fibrosis.”

“I am proud that the ATS recognizes and provides opportunities for patients and families to partner with the scientific community to improve lung health. Therapeutic and preventative approaches are urgently needed for patients with HPS, and I believe that this rare disease will have much to teach us about more common forms of pulmonary fibrosis as well,” said Dr. Young.

Donna Appell, RN, president and founder of the Hermansky-Pudlak Syndrome Network said, “We are extremely delighted with the news of Dr. Young’s R01 award from NIH. We are grateful to the ATS for allowing us to leverage our support to reach such a great outcome. Where else could you possibly have such a great return on investment?”

Building a future where patients breathe better

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